Aortic Occlusion for Resuscitation in Trauma and Acute Care Surgery (AORTA)
The Aortic Occlusion for Resuscitation in Trauma and Acute Care Surgery (AORTA) study is a prospective, multicenter observational trial examining the use of aortic occlusion (AO) during the acute resuscitation of trauma and acute care surgery patients in shock. AO may be performed through traditional open techniques or through endovascular approaches such as balloon occlusion. Despite increasing use of these methods, indications, practice patterns, and outcomes remain incompletely defined.
This study will collect standardized data from participating centers on adult patients (≥18 years) who undergo aortic occlusion during the acute phase of care. Data collected will include patient characteristics, mechanism and severity of injury, type and timing of aortic occlusion (open or endovascular), and in-hospital outcomes.
The primary objective is to evaluate outcomes following AO, including in-hospital mortality, neurologic outcomes, and complications. Secondary objectives include describing current practice patterns in AO utilization and identifying factors associated with successful outcomes. Data will be analyzed to characterize the clinical use of aortic occlusion better and inform future protocols for the management of patients with hemorrhagic shock.