A Multi-Institutional, Prospective Observational Study On Impact Of Pre-Hospital Whole Blood On Mortality In Severely Injured Trauma Patients
Hypothesis: The administration of any volume of whole blood in trauma patients before arrival to the hospital will reduce in-hospital mortality.
Study Aim(s)- Primary Aim: To evaluate use of pre-hospital administration of WB and in-ED WB transfusion in combination with BCT, versus patients who only received ED WB in combination with BCT, and associated outcomes on in-hospital mortality in significantly injured trauma patients who require MTP within the first 4 hours of arrival to the hospital.
Study Aim(s)-Secondary Aim: To evaluate the use of pre-hospital administration of WB and in-ED WB transfusion in combination with BCT, versus patients who only received pre-hospital crystalloid resuscitation or BCT and in-hospital WB transfusion in combination with BCT, and its associated outcomes on in-hospital mortality on significantly injured trauma patients who require MTP within the first 4 hours of arrival to the hospital.
Study Protocol
Data Collection
Consent Form
Study Design