• Post-Discharge Adherence with Venous Thromboembolism Prophylaxis after Orthopedic Trauma: Results from a Randomized Controlled Trial of Aspirin vs Low Molecular Weight Heparin (April 2018)

    Category: Acute Care Surgery, Cardiopulmonary Critical Care, Epidemiology, Extremity Fractures, Hand, Outcomes/Guidelines
    Bryce E. Haac, MD, Richard Van Besien, Nathan N. O’Hara, MHA, Gerard P. Slobogean, MD, MPH, Theodore T. Manson, MD, Robert V. O’Toole, MD, Herman Johal, MD, MPH, Peter Z. Berger, George B. Reahl, Dimitrius Marinos, Yasmin Degani, MPH, Daniel Mascarenhas, Daniel Connelly, Thomas M. Scalea, MD, and Deborah M. Stein
    CME 1 CME Credit(s)

    Learning Objectives:

    We sought to compare post-discharge adherence patterns with two common venous thromboembolism chemoprophylaxis regimens (low molecular weight heparin and aspirin) after orthopedic trauma and to identify risk factors for nonadherence.

    Impact Statement:

    Pulmonary embolism (PE) is one of the most common causes of death in trauma patients who survive beyond the first 24 hours after injury, and orthopedic trauma patient are at particularly high risk for venous thromboembolism (VTE). As a result, many trauma patients with orthopedic injuries are treated with chemoprophylaxis after discharge from their index admission. Nonadherence with chemoprophylaxis is known to be significantly associated with increased VTE risk. Unfortunately there is little quality data describing post-discharge adherence with the most common chemoprophylaxis regimens (low molecular weight heparin and aspirin) in this population. We conducted a randomized controlled trial in which we examined post-discharge adherence in this population, comparing adherence with these two regimens and identifying risk factors for nonadherence.

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    This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education through the joint providership of the American College of Surgeons and the American Association for the Surgery of Trauma. The American College of Surgeons is accredited by the ACCME to provide continuing medical education (CME) for physicians.

    AMA PRA Category 1 Credits™

    The American College of Surgeons designates this journal-based activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Of the AMA PRA Category 1 Credits™ listed above, a maximum of 1 credit meets the requirements for Self-Assessment.

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