The overall objective of this study was to identify the injury patterns, reversal strategies, and outcomes among patients taking novel oral anticoagulants. We hypothesized that patients taking novel oral anticoagulants would have worsened outcomes following trauma compared to patients anticoagulated with warfarin, aspirin or clopidogrel.
Trauma remains a leading cause of death among the elderly. The number of elderly trauma patients presenting on anticoagulants is on the rise and traditional anticoagulants such as warfarin and clopidogrel are associated with worsened outcomes among trauma patients particularly those with intracranial hemorrhage. However, the effect of newer anticoagulants such as dabagatran, rivaroxaban, and apixaban on the outcomes of trauma patients is unknown.
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