• Novel Oral Anticoagulants and Trauma: The Results of a Prospective AAST Multi-Institutional Trial (May 2017)

    Category: Epidemiology, Surgical Critical Care
    Leslie Kobayashi, MD, Galinos Barmparas, MD, Patrick Bosarge, MD, Carlos V. Brown, MD, Marko Bukur, MD, Matthew M. Carrick, MD, Richard D. Catalano, MD, Jan Holly-Nicolas, MD, Kenji Inaba, MD, Stephen Kaminski, MD, Amanda L. Klein, MD, Tammy Kopelman, MD, Eric J. Ley, MD, Ericca M. Martinez, Forrest O. Moore, MD, Jason Murry, MD, Raminder Nirula, MD, MPH, Douglas Paul, DO, Jacob Quick, MD, Omar Rivera, MD, Martin Schreiber, MD, Raul Coimbra, MD, PhD, and the AAST Multicenter Prospective Observational Study of Trauma Patients on Novel Oral Anticoagulants Study Group
    CME 1 CME Credit(s)

    Learning Objectives:

    The overall objective of this study was to identify the injury patterns, reversal strategies, and outcomes among patients taking novel oral anticoagulants. We hypothesized that patients taking novel oral anticoagulants would have worsened outcomes following trauma compared to patients anticoagulated with warfarin, aspirin or clopidogrel.

    Impact Statement:

    Trauma remains a leading cause of death among the elderly. The number of elderly trauma patients presenting on anticoagulants is on the rise and traditional anticoagulants such as warfarin and clopidogrel are associated with worsened outcomes among trauma patients particularly those with intracranial hemorrhage. However, the effect of newer anticoagulants such as dabagatran, rivaroxaban, and apixaban on the outcomes of trauma patients is unknown.

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    This activity has been planned and implemented in accordance with the Essential Areas and Policies of the Accreditation Council for Continuing Medical Education through the joint providership of the American College of Surgeons and the American Association for the Surgery of Trauma. The American College of Surgeons is accredited by the ACCME to provide continuing medical education (CME) for physicians.

    AMA PRA Category 1 Credits™

    The American College of Surgeons designates this journal-based activity for a maximum of 1 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Of the AMA PRA Category 1 Credits™ listed above, a maximum of 1 credit meets the requirements for Self-Assessment.

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