Peptic Ulcer Disease

The fellow should be able to:

• Demonstrate an understanding of the evaluation and etiology of peptic ulcer disease
• Describe the initial medical management of PUD
• Describe the indications for non-operative treatment of perforated ulcer disease
• Describe the indications and options for the surgical management of gastric ulcer disease
• Describe the indications and options for the surgical management of duodenal ulcer disease
• Describe the management of the “difficult duodenum”

Resources

• Topic Summary
• AAST Education Module - Perforated Peptic Ulcer
• Overview Article
  • Tarasconi A; Coccolini F; et al. Perforated and bleeding peptic ulcer: WSES guidelines. World J Emerg Surg. 2020 Jan 7;15:3. 
• Additional Resources
  • Boyd-Carson H; Doleman B; et al. National Emergency Laparotomy Audit Collaboration. Delay in Source Control in Perforated Peptic Ulcer Leads to 6% Increased Risk of Death Per Hour: A Nationwide Cohort Study. World J Surg. 2020 Mar;44(3):869-875. 
  • Chan KS; Wang YL; et al. Outcomes of omental patch repair in large or giant perforated peptic ulcer are comparable to gastrectomy. Eur J Trauma Emerg Surg. 2021 Dec;47(6):1745-1752. 
  • Gong EJ; Lee SJ; et al. Optimal Timing of Feeding After Endoscopic Hemostasis in Patients With Peptic Ulcer Bleeding: A Randomized, Noninferiority Trial (CRIS KCT0001019). Am J Gastroenterol. 2020 Apr;115(4):548-554. 
  • Odisho, T; Shahait, AA; et al. Outcomes of laparoscopic modified Cellan-Jones repair versus open repair for perforated peptic ulcer at a community hospital. Surg Endosc. 2023 Jan;37(1):715-722. 
• Multimedia Resources
  • SAGES video “Surgical Management of Perforated Peptic Ulcer Disease” 
  • SAGES video “Laparoscopic and Endoscopic Treatment for Peptic Ulcer Disease”