Approximately 3 million individuals suffer craniofacial trauma in the United States on a yearly basis,
and approximately 50% of all wounds presenting to emergency rooms involve the head and neck [1, 2].
Prophylactic antibiotics have been employed to decrease infectious complications; however, up to 60% of
antibiotics prescribed in the emergency department are inappropriate . While indications for prophylactic
antibiotic usage in facial fractures have been extensively studied, low overall data quality and sample size have
limited the development of clinical practice guidelines [4-16]. The aim of this study is to establish the optimal
duration of prophylactic antibiotics